Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human Tripeptidyl-peptidase I/TPP1 quantitates human Tripeptidyl-peptidase I/TPP1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Tripeptidyl-peptidase I/TPP1.
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CLN2, GIG1, LPIC, SCAR7, TPP-1, TPP1, UNQ267/PRO304
Gene ID : (Human) 1200
Gene symbol : TPP1
Protein Aliases : Cell growth-inhibiting gene 1 protein, growth-inhibiting protein 1, LPIC, lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease, TPP-1, TPP-I, Tripeptidyl aminopeptidase, tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I
UniProt ID (Human) O14773
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support