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Human VASN ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human Vasorin in serum, plasma, and cell culture supernatants.
The VASN gene encodes the protein vasorin, a type I transmembrane protein involved in cellular signaling, vascular development, and tissue repair. Vasorin is characterized by its expression in various tissues, including vascular endothelial cells and smooth muscle cells, where it functions to modulate cell proliferation and differentiation. It plays a significant role in the regulation of vascular remodeling and homeostasis by interacting with signaling molecules like transforming growth factor-beta (TGF-β), thereby influencing processes such as angiogenesis and wound healing. Vasorin is implicated in inhibiting TGF-β signaling pathways, which are crucial for maintaining vascular integrity and preventing excessive fibrosis during tissue repair. Dysregulation of VASN expression can contribute to pathological conditions, including cardiovascular diseases and cancer, where abnormal vascular remodeling and cell proliferation are evident. Research into vasorin continues to explore its functional mechanisms and potential therapeutic applications in diseases characterized by vascular dysregulation and tissue remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : SLITL2, UNQ314/PRO357/PRO1282, VASN
Gene ID : (Human) 114990
Gene symbol : VASN
Protein Aliases : Protein slit-like 2, slit-like 2, Vasorin
UniProt ID (Human) Q6EMK4
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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