A thermal cycler (also called thermocycler) is an instrument that employs precise temperature control and rapid temperature changes to conduct the polymerase chain reaction (PCR). PCR is used to create billions of copies of a DNA sequence for use in a wide array of downstream procedures including cloning, sequencing, expression analysis, and genotyping. Our engineers have been designing and manufacturing high-quality Applied Biosystems thermal cyclers since 1987; these instruments are renowned for their reliability, accuracy, and user-friendly interfaces.
Which thermal cycler is right for you?
| Most flexible and highest throughput |
Elegant design, smart choice |
For robust thermal cycling and diagnostic applications | Designed for easy robotic integration | |
| ProFlex™ PCR System Cloud enabled |
SimpliAmp™ Thermal Cycler Cloud enabled |
Veriti™ Thermal Cycler** | Automated Thermal Cycler (ATC) | |
![]() Demo request |
![]() Demo request |
![]() Demo request |
![]() Demo request |
|
| Block formats |
|
|
|
|
| Temperature optimization |
|
|
|
None |
| User interface | 8.4 in. touch screen | 8.4 in. touch screen | 6.5 in. touch screen | Automated via robotics; desktop software allows full integration |
| Sample throughput |
Up to 480,000 reactions | Up to 96 reactions | Up to 384 reactions | Up to 96 reactions |
| Max block ramp rate*** | 6.0°C/sec | 4.0°C/sec | 5.0°C/sec | 3.5°C/sec |
| Learn more | Learn more | Learn more | Learn more |
**Also available as an FDA Class 1/ CE-IVD labeled device, click here for details
***For information about how ramp rates are calculated, click here
Resources
Applied Biosystems Thermal Cycler, Plastics and Services Brochure
PCR and cDNA Synthesis Support Center
Tips and troubleshooting help
School of Molecular Biology, PCR Education
Technical content for new and experienced molecular biologists
Thermal Cycler Software and Firmware Files
Download the latest updates for your instrument
Interested in private label thermal cyclers?
Submit an inquiry
Service
We provide award-winning service options for all Applied Biosystems thermal cyclers.
Service plans
Support
Additional services available
Instrument qualification service: Have one of our engineers perform temperature qualifications at your site. You may also contact Instrument Services to purchase a temperature verification tool and perform the qualification yourself.
For Research Use Only. Not for use in diagnostic procedures.




