US HUPO 2026

Feb 21 - 25, 2026
St. Louis, Missouri

Join us at US HUPO 2026, Thermo Fisher Scientific booth #29 and Olink booth #28

Explore the latest breakthrough solutions, meet our experts, and learn what’s new. Don't miss our lunchtime seminar on Tuesday, February 24. Seating is limited, so be sure to arrive early. Lunch will be available while supplies last.


Schedule and solutions

Thermo Fisher Lunchtime Seminar

Date: Tuesday, February 24
Time: 12:30 p.m. - 1:30 p.m. CST

Room: Grand GH

 

Unlocking Biological Complexity with Advanced Proteomics

Recent advances in proteomics enable unprecedented depth, resolution, and functional insight. Single-cell proteomics, spatial omics, phosphoproteomics, chemoproteomics, immunopeptidomics, and interactomics now link molecular detail to biological context and disease relevance. This seminar showcases mass spectrometry workflows accelerating discovery and translation into biomarkers and therapies, featuring insights, innovations, and applications from leading laboratories. 

Oral presentation

Affinity-based Olink Proteomics Provides Insights into Organ- and Plasma-specific Proteomes

Parallel Session 04: Affinity Proteomics: Without Mass Spectrometry

Date: Monday, February 23, 2026

Time: 11:00 a.m. - 12:20 p.m. CST

Presenter: Ryan Lamers

Poster presentations

Monday, February 23, 2026 | 4:30 p.m. – 6:30 p.m. CST

417 - Expanding the Global Map of Protein Post Translational Modifications with Immunoaffinity Enrichment and nDIA Analysis on the Orbitrap Astral Mass Spec

Mukesh Kumar

425 - High Select Fe-NTA Magnetic Beads for Phosphopeptide Enrichment

Leigh Foster

441 - High-Throughput Screening of Molecular Glues Using Native Mass Spectrometry Followed by Cryo-EM Structure Determination

Weijing Liu

465 - The Secret Life of Proteins and Drugs Through the Lens of Proteome Thermal Stability

Tonya Pekar Hart

469 - Unlocking the Archived Proteome: Deep Spatial Analysis of FFPE Tissues in Minutes

Ellen Casavant

505 - Cutting-Edge Targeted Pathway Analysis: Advancing Functional Proteogenomics in Cancer Cells

Katherine Walker

523 - Alternative Fragmentation is Not Enough for Top-down MS and Intact Proteoform Characterization

Rafa Melani

525 - Expedient Electron Transfer Dissociation for Improved Glycoproteome Characterization

Rafa Melani

533 - Innovative Data-Independent Acquisition (DIA) Workflows for Protein–Nucleic acid Interactions in Living Cells

Yi He


Tuesday, February 24, 2026 | 4:30 p.m. – 6:30 p.m. CST

354 - An Automated Sequential Protein/DNA/RNA extraction Workflow for Comprehensive Multiomics Analysis from Cells and Tissue

Laure Jobert

372 - Advanced Enrichment and LC-MS Analysis for Detailed MHC-I Immunopeptidome Profiling

Anastasia Klenke

462 - Enhanced Sensitivity of the Orbitrap Astral Zoom Mass Spectrometer for Deeper Proteome Coverage in Single-Cell Proteomics Applications

Tonya Pekar Hart

468 - PTM Analysis with EThcD on an Orbitrap Excedion Pro Instrument

Tonya Pekar Hart

478 - Data-Independent Acquisition for Comprehensive Immunopeptidome Profiling on a Modified Orbitrap Astral Mass Spectrometer

Ellen Casavant

510 - A Novel Ion Source with Integrated Separation Column and Replaceable Emitters Facilitates Ultra High-Throughput Multiplex PRM-MS

Katherine Walker

566 - Complementarity Between Affinity-based Proteomics and Mass Spectrometry Workflows Enable Comprehensive Insights into Cancer Biology

Ryan Lamers

Olink Lunchtime seminar

Date: Monday, February 23
Time: 12:30 p.m. - 1:30 p.m. CST

Room: Grand GH

 

Explore the Human Proteome with Depth and Scale

Proteomics and multi-omics are reshaping our understanding of human biology, offering unprecedented insights into disease mechanisms and biomarker landscapes. This session will highlight how Olink’s Proximity Extension Assay (PEA) technology is uniquely positioned to support population-scale proteomic studies, bridging the gap from discovery research to clinical utility. The use of integrative analysis combining Olink HT with mass spectrometry analysis provides comprehensive data to identify unique protein signatures and to provide data-driven insights that propel precision medicine.


Thermo Scientific Orbitrap Astral Zoom Mass Spectrometer is engineered with a hybrid architecture that integrates a quadrupole mass filter with two high-resolution, accurate-mass (HRAM) analyzers: the Orbitrap analyzer and the Astral analyzer. This dual-analyzer configuration enables parallel and complementary ion analysis, supporting advanced acquisition modes such as narrow-window data-independent acquisition (nDIA) and Simultaneous Quantitation and Discovery (SQUAD) workflows. By combining high scan speed, high sensitivity, and accurate mass measurement, the Orbitrap Astral Zoom MS delivers increased throughput, deeper molecular coverage, and robust quantitative performance. These capabilities support demanding workflows across proteomics, metabolomics, lipidomics, structural biology, and biopharmaceutical research, enabling confident identification and precise quantitation in complex samples.

Thermo Scientific Orbitrap Excedion Pro hybrid Mass Spectrometers build on the proven quadrupole-Orbitrap platform, delivering enhanced sensitivity, extended dynamic range, and fast, high-efficiency electron-based fragmentation with optional field-upgrade capability. These systems introduce unique performance enhancements that elevate routine analyses into high-confidence, high-impact results. Engineered for biopharma, metabolomics, proteomics, and structural biology workflows, Orbitrap Excedion Pro hybrid mass spectrometers redefine benchtop analytical performance—enabling deeper characterization, improved quantitation, and greater experimental flexibility for advanced research and development.

The Thermo Scientific Stellar Mass Spectrometer introduces groundbreaking technology that merges robust quantitation with the precision of rapid full scan MSn acquisition, significantly enhancing laboratory productivity. This mass spectrometer sets a new standard for targeted quantitation, allowing for more efficient, confident, and cost-effective progression of biomarker candidates from discovery to validation. It features advancements in scalability, throughput, sensitivity, specificity, and overall productivity.

The Thermo Scientific AccelerOme Automated Sample Preparation Platform, with factory-supplied reagents and kits,  intuitive software and a unique experimental design experience, transforms proteomics sample preparation.

Designed for researchers pursuing their next scientific breakthrough, the Thermo Scientific Vanquish Neo UHPLC System is ideal for LC-MS applications in proteomics, precision medicine, translational research, and more. Combine with Thermo Scientific PepMap Neo nano-flow LC columns for unmatched efficiency and robust performance for shallow gradients, high-throughput applications, and everything in between.

The Sequential Protein/DNA/RNA Extraction Kit represents an exceptional multi-omics solution designed for the sequential purification of high-quality protein, DNA, and RNA from the same cell or tissue sample. This bead-based extraction system addresses the critical need for comprehensive molecular analysis when sample availability is limited or when studying heterogeneous specimens.

The Thermo Scientific Pierce MHC Class I Antibody Coupling Kit is a comprehensive kitted solution designed for magnetic immunoprecipitation of MHC Class I protein and peptide complexes. It provides all necessary components for antibody coupling and peptide enrichment required for immunopeptidomic studies. This kit features an optimized protocol with guidance all the way through LC-MS analysis.

Thermo Scientific TMTpro Label Reagents are the next generation of tandem mass tags, designed to increase the level of sample multiplexing without compromising on protein identification and quantitation. TMTpro deuterated label reagents enable multiplexing of up to 35 samples, for even greater throughput for protein identification and quantitative analysis by tandem mass spectrometry (MS/MS).

For Research Use Only. Not for use in diagnostic procedures.