Molecular Assessment of Rejection in Pediatric Heart Transplantation: A Complement to Histopathology Webinar

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In this on-demand webinar, Dr. Defne Magnetta and Dr. Nicoleta Arva discuss the ISHLT grading system for acute rejection in pediatric heart transplantation, the strengths and pitfalls of histopathology, and how the MMDx™ Heart test can help provide a more comprehensive and accurate diagnosis by combining the power of traditional histopathology with molecular techniques to identify specific genetic and molecular changes associated with diseases.

Watch the webinar to discover how MMDx Heart can provide valuable information in cases of severe cellular rejection following an organ transplant, helping to manage antibody-mediated rejection (ABMR), guide treatment decisions, and improve patient outcomes.

Learning Objectives:

  • To review the ISHLT grading system for acute rejection in pediatric heart transplantation and discuss the strengths and pitfalls of histopathology
  • To discuss the additional information gained from MMDx in cases of severe cellular rejection
  • To illustrate the way in which MMDx and histopathology utilized together may help guide management of ABMR

 


Speakers:

Dr. Defne Magnetta
Ann & Robert H. Lurie Children's Hospital of Chicago

Dr. Nicoleta Arva 
Ann & Robert H. Lurie Children's Hospital of Chicago
 

Moderator:

Heather Manion 
Thermo Fisher Scientific
 

Recorded:
May 18, 2023

Moderator:

Heather Manion

Heather Manion, MSN, RN, CCTC
Medical Science Liaison
Thermo Fisher Scientific

Guest Speakers:

Defne Magnetta, MD
Pediatric Cardiologist
Ann & Robert H. Lurie Children’s Hospital of Chicago
Chicago, Illinois, USA

Nicoleta Arva, MD, PhD
Pediatric Pathologist
Ann & Robert H. Lurie Children’s Hospital of Chicago
Chicago, Illinois, USA

Disclaimers

Disclaimers:

MMDx Heart is a test that was developed and validated by Kashi Clinical Laboratories, Inc. The laboratory developed test is used for clinical
purposes by the CLIA-certified laboratory performing the test. This test has not been cleared or approved by the US FDA or CE-marked in the EU
as an in vitro diagnostic test.

All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. MMDx and Molecular Microscope are
trademarks of Transcriptome Sciences Inc.