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Invitrogen
CD9 Monoclonal Antibody (Ts9)
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FIGURE: 1 / 53
CD9 Antibody (10626D) in WB
International journal of oncology 2023 -
Morphology, size distribution, concentration and protein profiles of exosomes from HNSCC cell lines. Supernatants from HNSCC cell lines were collected and exosomes were isolated on mini-size exclusion chromatography columns. (A) Exosomes from UM-SCC-11B (11B), UM-SCC-14C (14C) and UM-SCC-22B (22B) show the typical vesicular shape and size in TEM images. Scale bar, 100 nm. (B) Western blotting was performed ... View More
Product Details
10626D
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Ts9
Immunogen
CD9 purified from HeLa cells
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
purified
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient
RRID
Product Specific Information
The Exosome - anti-CD9 antibody recognizes the CD9/p24 antigen (~24 kDa), a member of the tetraspanin family. The antibody has been verified for western blotting of cellular and exosomal CD9 antigen.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5H9; 5H9 antigen; antigen CD9; BA-2/p24 antigen; BA2; BTCC-1p; CD9; CD9 antigen; CD9 antigen (p24); Cell growth-inhibiting gene 2 protein; GIG2; Leukocyte antigen MIC3; motility related protein-1; Motility-related protein; MRP-1; p24; sCD 9; sCD9; soluble CD 9; soluble CD9; Tetraspanin-29; Tetraspanin29; Tspan-29; unnamed protein product
Gene Aliases: BTCC-1; CD9; DRAP-27; GIG2; MIC3; MRP-1; TSPAN-29; TSPAN29
UniProt ID: (Human) P21926
Entrez Gene ID: (Human) 928
cell adhesion
single fertilization
fusion of sperm to egg plasma membrane
nervous system development
cell proliferation
negative regulation of cell proliferation
glial cell migration
oligodendrocyte development
myoblast fusion involved in skeletal muscle regeneration
cell differentiation
platelet activation
paranodal junction assembly
receptor internalization
sperm-egg recognition
cellular response to low-density lipoprotein particle stimulus
negative regulation of platelet aggregation
regulation of macrophage migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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