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Proteintech
Fibulin 5 Polyclonal Antibody
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Product Details
12188-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fibulin 5 Fusion Protein Ag2859 (186-448 aa encoded by BC022280)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Amount
55.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody got 50 kDa or 66 kDa band in western blotting, the 66 kDa corresponding to fully glycosylated protein.
Immunogen sequence: GSYSCTCNP GFTLNEDGRS CQDVNECATE NPCVQTCVNT YGSFICRCDP GYELEEDGVH CSDMDECSFS EFLCQHECVN QPGTYFCSCP PGYILLDDNR SCQDINECEH RNHTCNLQQT CYNLQGGFKC IDPIRCEEPY LRISDNRCMC PAENPGCRDQ PFTILYRDMD VVSGRSVPAD IFQMQATTRY PGAYYIFQIK SGNEGREFYM RQTGPISATL VMTRPIKGPR EIQLDLEMIT VNTVINFRGS SVIRLRIYVS QYPF (186-448 aa encoded by B C022280)
Target Information
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 50kD; similar to human S1-5 encoded by GenBank Accession Number U03877; DANCE; Developmental arteries and neural crest EGF-like protein; Embryonic vascular EGF repeat-containing protein; embryonic vascular EGF-like repeat-containing protein; EVEC; FBLN5; FIBL-5; Fibulin-5; FLJ90059; testis tissue sperm-binding protein Li 75n; unnamed protein product; UP50; Urine p50 protein
Gene Aliases: A55; ADCL2; ARCL1A; ARMD3; CMT1H; DANCE; EVEC; FBLN5; FIBL-5; HNARMD; UNQ184/PRO210; UP50
UniProt ID: (Human) Q9UBX5, (Rat) Q9WVH8, (Mouse) Q9WVH9
Entrez Gene ID: (Human) 10516, (Rat) 29158, (Mouse) 23876
negative regulation of transcription from RNA polymerase II promoter
cell adhesion
cell-matrix adhesion
negative regulation of angiogenesis
extracellular matrix organization
positive regulation of osteoblast proliferation
protein localization to cell surface
positive regulation of transcription from RNA polymerase II promoter
secretion
elastic fiber assembly
intramembranous bone growth
regulation of removal of superoxide radicals
regulation of cell growth
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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