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Proteintech
GlnRS Polyclonal Antibody
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Product Details
12645-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GlnRS Fusion Protein Ag3375 (362-717 aa encoded by BC016634)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VKYTPHHRT GDKWCIYPTY DYTHCLCDSI EHITHSLCTK EFQARRSSYF WLCNALDVYC PVQWEYGRLN LHYAVVSKRK ILQLVATGAV RDWDDPRLFT LTALRRRGFP PEAINNFCAR VGVTVAQTTM EPHLLEACVR DVLNDTAPRA MAVLESLRVI ITNFPAAKSL DIQVPNFPAD ETKGFHQVPF APIVFIERTD FKEEPEPGFK RLAWGQPVGL RHTGYVIELQ HVVKGPSGCV ESLEVTCRRA DAGEKPKAFI HWVSQPLMCE VRLYERLFQH KNPEDPTEVP GGFLSDLNLA SLHVVDAALV DCSVALAKPF DKFQFERLGY FSVDPDSHQG KLVFNRTVTL KEDPGKV (362-717 aa encoded by BC016634 )
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GlnRS; Glutamine--tRNA ligase; glutamine-tRNA ligase; glutamine-tRNA synthetase; Glutaminyl-tRNA synthetase; unnamed protein product
Gene Aliases: 1110018N24Rik; 1200016L19Rik; C80286; GLNRS; MSCCA; PRO2195; QARS; QARS1; RGD1562301
UniProt ID: (Human) P47897, (Rat) Q66H61, (Mouse) Q8BML9
Entrez Gene ID: (Human) 5859, (Rat) 290868, (Mouse) 97541
translation
tRNA aminoacylation for protein translation
glutaminyl-tRNA aminoacylation
brain development
negative regulation of stress-activated MAPK cascade
tRNA aminoacylation
negative regulation of transcription, DNA-templated
negative regulation of apoptotic signaling pathway
negative regulation of apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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