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Proteintech
Cadherin-18 Polyclonal Antibody
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Product Details
13091-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cadherin-18 Fusion Protein Ag3675 (25-382 aa encoded by BC031051)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Amount
58.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TAHHSSIKV MRNQTKHIEG ETEVHHRPKR GWVWNQFFVL EEHMGPDPQY VGKLHSNSDK GDGSVKYILT GEGAGTIFII DDTTGDIHST KSLDREQKTH YVLHAQAIDR RTNKPLEPES EFIIKVQDIN DNAPKFTDGP YIVTVPEMSD MGTSVLQVTA TDADDPTYGN SARVVYSILQ GQPYFSVDPK TGVIRTALHN MDGEAREHYS VVIQAKDMAG QVGGLSGSTT VNITLTDVND NTPRFPQKHY QLYVPESAQV GSAVGKIKAN DADTGSNADM TYSIINGDGM GIFSISTDKE TREGILSLKK PLNYEKKKSY TLNIEGANTH LDFRFSHLGP FKDATMLKII VGDVDEPPL (25-382 aa encoded by BC031051)
Target Information
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cadherin; Cadherin 14; cadherin 18, type 2; Cadherin-14; Cadherin-18; cadherin-like 24; Cadherin14; Cadherin18; ey-cadherin; unnamed protein product
Gene Aliases: CDH14; CDH14L; CDH18; CDH24
UniProt ID: (Human) Q13634
Entrez Gene ID: (Human) 1016
cell morphogenesis
cell-cell junction assembly
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell migration
adherens junction organization
cell-cell adhesion mediated by cadherin
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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