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Invitrogen
gamma Catenin Monoclonal Antibody (PG-11E4)
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FIGURE: 1 / 24
gamma Catenin Antibody (13-8500) in ICC/IF
Immunofluorescence analysis of Gamma-Catenin was performed using 70% confluent log phase CACO2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Gamma-Catenin / Plakoglobin (PG-11E4) Mouse Monoclonal Antibody (Product # 13-8500) at 1:250 dilution in0.1%... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
13-8500
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
PG-11E4
Immunogen
Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; desmoplakin III; desmoplakin-3; desmosomal protein 3; gamma-catenin; OTTHUMP00000164735; unnamed protein product
Gene Aliases: CTNNG; D930025P04Rik; DP3; DPIII; PDGB; PG; PKGB
UniProt ID: (Human) P14923, (Mouse) Q02257
Entrez Gene ID: (Human) 3728, (Mouse) 16480
transcription coactivator activity
structural molecule activity
protein binding
ligand-dependent nuclear receptor binding
protein phosphatase binding
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
microtubule cortical anchor activity
protein kinase binding
macromolecular complex binding
protein tyrosine kinase binding
positive regulation of cell-matrix adhesion
desmosome assembly
cell adhesion
cell migration
regulation of cell proliferation
positive regulation of protein import into nucleus
negative regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
positive regulation of axon extension
positive regulation of transcription from RNA polymerase II promoter
detection of mechanical stimulus
canonical Wnt signaling pathway
endothelial cell-cell adhesion
cellular response to indole-3-methanol
protein localization to plasma membrane
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
positive regulation of canonical Wnt signaling pathway
cell-cell adhesion
regulation of ventricular cardiac muscle cell action potential
positive regulation of cellular protein localization
skin development
cell-cell junction organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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