Search
Proteintech
IGSF11 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
14003-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IGSF11 Fusion Protein Ag5094 (262-430 aa encoded by BC034411)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GAFFYWRSK NKEEEEEEIP NEIREDDLPP KCSSAKAFHT EISSSDNNTL TSSNAYNSRY WSNNPKVHRN TESVSHFSDL GQSFSFHSGN ANIPSIYANG THLVPGQHKT LVVTANRGSS PQVMSRSNGS VSRKPRPPHT HSYTISHATL ERIGAVPVMV PAQSRAGSLV (262-430 aa encoded by BC034411)
Target Information
Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brain and testis-specific immunoglobin superfamily protein; Brain and testis-specific immunoglobulin superfamily protein; Bt-IGSF; cancer/testis antigen 119; CXADR like 1; IgSF11; Immunoglobulin superfamily member 11; immunoglobulin superfamily, member 13; unnamed protein product; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3
Gene Aliases: 1700025L02Rik; BT-IgSF; BTIGSF; CT119; CXADRL1; IGSF11; Igsf13; VSIG3
UniProt ID: (Human) Q5DX21, (Rat) Q5U2P2, (Mouse) P0C673
Entrez Gene ID: (Human) 152404, (Rat) 303926, (Mouse) 207683
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
regulation of synaptic plasticity
cell-cell adhesion via plasma-membrane adhesion molecules
trans-synaptic signaling
positive regulation of long-term synaptic potentiation
regulation of presynapse assembly
regulation of growth
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support