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Proteintech
OMA1 Polyclonal Antibody
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Product Details
17116-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OMA1 Fusion Protein Ag10803 (361-524 aa encoded by BC012915)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to OMA1.
Immunogen sequence: ICPRDSLAL LCQWIQSKLQ EYMFNRPYSR KLEAEADKIG LLLAAKACAD IRASSVFWQQ MEFVDSLHGQ PKMPEWLSTH PSHGNRVEYL DRLIPQALKI REMCNCPPLS NPDPRLLFKL STKHFLEESE KEDLNITKKQ KMDTLPIQKQ EQIPLTYIVE KRTGS (361-524 aa encoded by BC012915)
Target Information
OMA1 (Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family. It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants, and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Metalloendopeptidase OMA1, mitochondrial; Metalloprotease-related protein 1; MPRP-1; OMA1 homolog, zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; overlapping activity with M-AAA protease; Overlapping with the m-AAA protease 1 homolog; unnamed protein product; zinc metallopeptidase OMA1
Gene Aliases: 2010001O09Rik; DAB1; MPRP-1; MPRP1; OMA1; peptidase; YKR087C; ZMPOMA1
UniProt ID: (Human) Q96E52
Entrez Gene ID: (Human) 115209
mitophagy
diet induced thermogenesis
glucose metabolic process
translational initiation
proteolysis
misfolded or incompletely synthesized protein catabolic process
lipid metabolic process
mitochondrion organization
negative regulation of mitochondrial fusion
protein autoprocessing
zymogen activation
mitochondrial respiratory chain complex assembly
cellular response to stress
mitochondrial protein processing
cristae formation
positive regulation of apoptotic process
protein localization to mitochondrion
energy homeostasis
positive regulation of cold-induced thermogenesis
integrated stress response signaling
HRI-mediated signaling
positive regulation of mitophagy
regulation of cristae formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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