Thermo Scientific™

DSG (disuccinimidyl glutarate)

Catalog number: 20593
Thermo Scientific™

DSG (disuccinimidyl glutarate)

Catalog number: 20593
Catalog Number
20593
Unit Size
50 mg
Price (USD)
Price: 119.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
10 x 1 mg
Price (USD)
Price: 144.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
2059350 mg
Price: 119.00
Your Price:
-
A3539210 x 1 mg
Price: 144.00
Your Price:
-
Product Overview
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Thermo Scientific Pierce DSG is a water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors. The NHS ester is the simplest and most commonly used reactive group for crosslinking and labeling proteins and peptides. NHS esters react with primary amines on the N-termini of peptides and the  amine of lysine residues, forming a stable, covalent amide bond and releasing the NHS group.

Thermo Scientific No-Weigh products are specialty reagents provided in a pre-aliquoted format. The pre-weighed packaging prevents the loss of reagent reactivity and contamination over time by eliminating the repetitive opening and closing of the vial. The format enables use of a fresh vial of reagent each time, eliminating the hassle of weighing small amounts of reagents and reducing concerns over reagent stability.

Features of disuccinimidyl glutarate:

Reactive groups: NHS ester (both ends)
Reactive towards: amino groups (primary amines)
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Membrane-permeable, allowing for intracellular crosslinking
• Can increase crosslinking efficiency compared to DSS in some applications

Product References
Crosslinker Application Guide -- search for recent literature references for this product

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Homobifunctional
Reactive Moiety
NHS Ester
Spacer
Short
Form
Powder
Quantity
50 mg
Type
Crosslinker
Solubility
DMF, DMSO

Contents & Storage

Store desiccated at 4°C. Shipped at ambient temperature.