Nalgene™ Square Wide-Mouth Large PPCO Bottle with Closure: Autoclavable - FAQs

PPCO bottles/tubes are not recommended for sterilization by radiation. Polycarbonate bottles/tubes would be a suitable alternative if radiation sterilization is desired.

This was a consequence of design and engineering limitations, and there was no practical way to incorporate the same level of seal integrity as our certified leakproof containers. While in many cases, they still hold up well to liquid containment applications, they have not been tested specifically for that purpose, and thus would be the responsibility of the customer to perform validation and risk management studies if necessary.