MagnaBind™ Streptavidin Beads
Looking for a higher binding capacity streptavidin magnetic bead with greater flexibility? Try our Pierce Streptavidin Magnetic Beads. Pierce Magnetic beads accelerate throughput through validated and optimized automated methods and provide premium performance with manual methods. Please contact us with any questions.
MagnaBind™ Streptavidin Beads
Thermo Scientific™

MagnaBind™ Streptavidin Beads

Enable benchtop magnetic affinity purification with these ligand-coated (streptavidin, Protein A and G, GAM IgG, GAR IgG) magnetic particles and magnet separators.
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Catalog NumberQuantity
213445 mL
Catalog number 21344
Price (USD)
666.00
Each
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Quantity:
5 mL
Request bulk or custom format
Price (USD)
666.00
Each
Add to cart

Thermo Scientific MagnaBind Streptavidin Beads are convenient for affinity purification or separation methods involving of biotin-labeled molecules. To remove the MagnaBind Beads from the suspension, an external magnetic field is used.

Features of MagnaBind Streptavidin Beads:

  • Composition: Silanized iron oxide
  • Magnetization: 25-35EMU/g
  • Type of Magnetization: Superparamagnetic (no magnetic memory)
  • Surface Area: >100m2/g
  • Bead Size: 1-4μm diameter
  • Settling Rate: 4% in 30 minutes
  • Effective Density: 2.5g/mL
  • Number of Beads: 1 x 108 beads/mg
  • pH Stability: Aqueous solution, above pH 4.0
  • Concentration: 5 mg/mL

Streptavidin is a 60kDa protein from Streptomycetes avidinii. The protein is a tetramer having four biotin-binding sites. Unlike avidin, streptvidin has a low isoelectric point (pI=5) and no carbohydrate groups, resulting in low nonspecific binding. The high-affinity interaction between streptavidin and biotin cannot be dissociated efficiently except with very harsh conditions, such as boiling in sample loading buffer for SDS-PAGE or 8M guanidine HCl, pH 1.5. Consequently, it is often possible to elute binding partners in an interaction complex without also eluting the biotinylated component.

Applications:

  • Cell sorting using either positive or negative selection
  • Protein purification or immunoassays using either direct or indirect methods
For Research Use Only. Not for use in diagnostic procedures.
Specifications
ConcentrationSlurry: 5 mg/mL
DescriptionMagnaBind Streptavidin Beads
Ligand TypeStreptavidin
Product LineMagnaBind™
Quantity5 mL
Volume (Metric)5 mL
ColorBrown
Diameter (Metric)1 to 4 μm
For Use With (Application)Affinity Purification
Product TypeStreptavidin Magnetic Beads
Unit SizeEach
Contents & Storage
Upon receipt store product at 4°C. Do not freeze product. Product is shipped at ambient temperature.

Frequently asked questions (FAQs)

What are the differences between Pierce Streptavidin Magnetic Beads and MagnaBind Streptavidin Beads?

Pierce Streptavidin Magnetic Beads are homogeneous, non-aggregating, pre-blocked, iron oxide, superparamagnetic microparticles encapsulated with a proprietary polymer surface (no exposed iron, bead size of approximately 1 (0.5-1.5) µm, concentration 10 mg/mL). Pierce Streptavidin Magnetic Beads can be used in manual or automated applications (using KingFisher 96 and KingFisher Flex instruments, for example).
MagnaBind Streptavidin Beads are also superparamagnetic particles, but are heterogeneous aggregates made of silanized iron oxide (bead size approximately 1-4 µm, concentration 5 mg/mL). MagnaBind Streptavidin Beads can only be used in manual applications.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

Can I centrifuge the MagnaBind Streptavidin Beads and Thermo Scientific Streptavidin Magnetic Beads?

No, centrifuging causes the formation of irreversible aggregates which greatly reduces binding capacity.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

Can I freeze the MagnaBind Streptavidin Beads and Thermo Scientific Streptavidin Magnetic Beads?

No, freezing or drying will cause the beads to aggregate and lose binding activity. Store the beads only at 4 degrees C.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

What are the average sizes of your streptavidin magnetic beads?

Thermo Scientific Streptavidin Magnetic Beads average about 1 micron in daimeter ranging from about 0.5-1.5 microns while MagnaBind Streptavidin Beads are heterogenous averaging 1 - 4 microns.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

Are the MagnaBind Streptavidin Beads and Thermo Scientific Streptavidin Magnetic Beads sterile?

No, neither the MagnaBind Streptavidin Beads nor the Thermo Scientific Streptavidin Magnetic Beads are sterilized. However, they are both supplied in solutions containing sodium azide to prevent bacterial growth.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.