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Proteintech
LRRC32 Polyclonal Antibody
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Product Details
26021-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LRRC32 Fusion Protein Ag23423 (477-662 aa encoded by BC070079)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PGLEVATGA LGGLEASLEV LALQGNGLMV LQVDLPCFIC LKRLNLAENR LSHLPAWTQA VSLEVLDLRN NSFSLLPGSA MGGLETSLRR LYLQGNPLSC CGNGWLAAQL HQGRVDVDAT QDLICRFSSQ EEVSLSHVRP EDCEKGGLKN INLIIILTFI LVSAILLTTL AACCCVRRQK FNQQYKA (477-662 aa encoded by BC070079 )
Target Information
GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GARP; Garpin; Glycoprotein A repetitions predominant; Leucine-rich repeat-containing protein 32; Transforming growth factor beta activator LRRC32
Gene Aliases: AI426318; CPPRDD; D11S833E; D11S833Eh; D7H11S833E; EG434215; GARP; LRRC32
UniProt ID: (Human) Q14392, (Mouse) G3XA59
Entrez Gene ID: (Human) 2615, (Mouse) 434215
negative regulation of cytokine production
transforming growth factor beta receptor signaling pathway
positive regulation of gene expression
negative regulation of transforming growth factor beta receptor signaling pathway
establishment of protein localization to extracellular region
negative regulation of activated T cell proliferation
secondary palate development
negative regulation of cytokine secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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