Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains)자세히 알아보기
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카탈로그 번호
수량
26101
500 mg
카탈로그 번호 26101
제품 가격(KRW)
264,000
온라인 행사
Ends: 31-Dec-2025
293,000
할인액 29,000 (10%)
Each
카트에 추가하기
수량:
500 mg
대량 주문 또는 맞춤형 요청
제품 가격(KRW)
264,000
온라인 행사
Ends: 31-Dec-2025
293,000
할인액 29,000 (10%)
Each
카트에 추가하기
Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.
Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):
• Simple—one-step conversion of amines to sulfhydryls • Specific—selective and spontaneous modification of primary amines at pH 7-10 • Preserves positive charge to maintain protein solubility
Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.
Flexible—incorporates a five-atom spacer arm to reduce steric hindrance • Soluble—preserves the original positive charge to preserve protein solubility
For Research Use Only. Not for use in diagnostic procedures.
사양
형태Powder
라벨 유형Conjugating Groups
라벨 또는 염료Sulfhydryl Group
제품라인Pierce
수량500 mg
용해도DMF, DMSO
화학물질 반응성Amine
제품 유형Thiophilic Adsorption Kit
스페이서Short (<10 Å)
Unit SizeEach
구성 및 보관
Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature
자주 묻는 질문(FAQ)
How long and at what temperature can the Pierce Traut's Reagent (2-iminothiolane) (Cat. No. 26101) be stored in acidic solution devoid of primary amines?
We do not recommend storing the Traut’s Reagent in solution. This reagent is more stable in solution than others crosslinkers because hydrolysis takes place at a slower rate. Yet, its hydrolysis will inevitably occur with time if it is in solution. Therefore, to ensure a better crosslinking efficiency, we recommend preparing a fresh solution each time and storing the Traut's reagent as a powder at 4°C. Unfortunately, we do not have stability data of this reagent in a solution.
Can you provide the shelf-life for Traut's Reagent (2-iminothiolane)?
Traut's Reagent (2-iminothiolane) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.