Thermo Scientific™

Pierce™ Traut's Reagent (2-iminothiolane)

Catalog number: 26101
Thermo Scientific™

Pierce™ Traut's Reagent (2-iminothiolane)

Catalog number: 26101
Catalog Number
26101
Unit Size
500 mg
Price (USD)
Price: 195.00
Your Price:
Quantity
Catalog NumberUnit SizePrice (USD)Quantity
26101500 mg
Price: 195.00
Your Price:
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Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.

Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):

Simple—one-step conversion of amines to sulfhydryls
Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility

Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.

Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
Soluble—preserves the original positive charge to preserve protein solubility

Related Products
Pierce™ SATA
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine
Label or Dye
Sulfhydryl Group
Label Type
Conjugating Groups
Product Line
Pierce™
Spacer
Short
Form
Powder
Quantity
500 mg
Product Type
Thiophilic Adsorption Kit
Solubility
DMF, DMSO

Contents & Storage

Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature