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Invitrogen
MAG Polyclonal Antibody
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FIGURE: 1 / 21
MAG Antibody (34-6200) in WB
Western Blot was performed using Anti-MAG Polyclonal Antibody (Product # 34-6200) and a 100 kDa band corresponding to Myelin-associated glycoprotein was observed across brain and cerebellum tissues which are reported to be positive for MAG expression when compared to other tissues such as stomach, large intestine and skeletal muscle. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Rat Brain (Lane 2), Mouse Cerebellum (Lane 3), Rat Cerebellum (Lane 4), Mouse Stomach (Lane 5), Mouse Large Intestine (Lane 6), Mouse Skeletal Muscle (La... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
34-6200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Human S/L-MAG fusion protein with a C-terminal region insert.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brain neuron cytoplasmic protein 3; brain-specific neuronal polypeptide 1B236; brain-specific protein; myelin-associated glycoprotein; myelin-associated glycoprotein precursor; S-MAG (C-term.); sialic acid binding Ig-like lectin 4A; sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; siglec-4a; unnamed protein product
Gene Aliases: 1B236; GMA; S-MAG; SIGLEC-4A; SIGLEC4; SIGLEC4A; SPG75
UniProt ID: (Human) P20916, (Mouse) P20917, (Rat) P07722
Entrez Gene ID: (Human) 4099, (Mouse) 17136, (Rat) 29409
cell adhesion
nervous system development
negative regulation of neuron projection development
substantia nigra development
central nervous system myelination
negative regulation of axon extension
positive regulation of myelination
central nervous system myelin formation
myelination
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of astrocyte differentiation
cellular response to mechanical stimulus
cell-cell adhesion
transmission of nerve impulse
axon regeneration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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