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Invitrogen
ANGPTL4 Polyclonal Antibody
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FIGURE: 1 / 17
ANGPTL4 Antibody (40-9800) in IHC (P)
Immunohistochemistry analysis of ANGPTL4 showing staining in the cytoplasm and nucleus of paraffin-embedded mouse liver tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room te... View More
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
.jpg?time=20220826?time=20220826 "ANGPTL4 Antibody (40-9800) in WB")
Product Details
40-9800
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from an internal region of the human ANGTPL4 protein, which differs from rat and mouse by one and two conservative amino acid replacements, respectively
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 425O18-1; angiopoietin-like protein 4; ANGPTL2; Angptl4; contains fibrinogen-like domain; Fasting-i; fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; secreted protein; secreted protein Bk89; unnamed protein product
Gene Aliases: ARP4; Bk89; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; Pp1158; TGQTL; UNQ171
UniProt ID: (Human) Q9BY76, (Mouse) Q9Z1P8, (Rat) Q6TMA8
Entrez Gene ID: (Human) 51129, (Mouse) 57875, (Rat) 362850
response to hypoxia
blood coagulation
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of apoptotic process
protein unfolding
negative regulation of fatty acid biosynthetic process
positive regulation of angiogenesis
positive regulation of multicellular organismal process
triglyceride homeostasis
regulation of chylomicron remodeling
regulation of triglyceride transport
cellular response to starvation
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
negative regulation of endothelial cell apoptotic process
regulation of lipid metabolic process
negative regulation of catalytic activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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