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Invitrogen
Phospho-NFkB p65 (Ser536) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-NFkB p65 (Ser536) Antibody (44-712G) in WB
Western blot analysis of lysates prepared from HeLa cells using rabbit anti- NFKB (pS536) antibody (Product # 44-712G). HeLa cells were left untreated (lane 1) or treated with TNF-alpha and ALLN (lanes 2-5) were resolved on a 10% polyacrylamide gel and transferred to PVDF. Prior to incubation with the primary antibody, the membrane was incubated with no peptide (lane 2), the non-phosphopeptide corresponding... View More
Product Details
44-712G
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human NFkB that contains serine 536.
Conjugate
Form
Liquid
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
RRID
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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