Acetyl-Histone H3 (Lys9 + Lys14) Antibody

Catalog number: 491010

Invitrogen™  Related applications: Cellular Imaging | Chromatin Biology

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Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Reactivity: Human
Validated Application: ELISA, Chromatin Immunoprecipitation, Immunofluorescence
Host Species: Rabbit
SubClass (Isotype): IgG
Clonality: Polyclonal
Target Gene: H3K9/14ac
Target Molecule: Peptides
Gene ID: 8290
Gene Symbol: HIST3H3
Accession Number: NM_003493
Label or Dye: Unconjugated
Target Modification State: Acetylated
Purification: Affinity Purified
Concentration: 1.1 mg⁄ml
Color: Unconjugated
Form: Frozen
High Throughput Compatibility: Not High Throughput-Compatible (Manual)
Neutralizing Antibody: No
Product Size: 44 µg
Volume (Metric): 40 µl
Shipping Condition: Dry Ice

Contents & storage

Store at -20°C⁄ -80°C. Avoid multiple freeze-thaw cycles. Guaranteed stable for 6 months when properly stored.

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Manuals & protocols

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