Search

  • Contáctenos
  • Orden Rápida

AbboMax

S100 Monoclonal Antibody (15E2E2)

View all (12) S100 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

Product Details

500-6824

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-1 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

2-10 µg/mL
-
Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

15E2E2

Immunogen

Purified bovine brain S100 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive control: Melanoma or Schwannoma

Cellular location: Cytoplasmic.

Target Information

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Protein S100-A1; Protein S100-B; S 100; S-100 calcium-binding protein, beta chain; S-100 protein alpha chain; S-100 protein beta chain; S-100 protein subunit alpha; S-100 protein subunit beta; S100 alpha; S100 calcium-binding protein A1; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S100 protein, alpha polypeptide; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100alpha; S100B; unnamed protein product

View more View less

Gene Aliases: AI266795; AI850290; Bpb; NEF; S100; S100-alpha; S100-B; S100A; S100A1; S100B; S100beta; S100P

View more View less

UniProt ID: (Bovine) P02639, (Human) P23297, (Bovine) P02638, (Human) P04271, (Rat) P35467, (Mouse) P56565, (Mouse) P50114, (Rat) P04631

View more View less

Entrez Gene ID: (Bovine) 528735, (Human) 6271, (Bovine) 525716, (Human) 6285, (Rat) 295214, (Mouse) 20193, (Mouse) 20203, (Rat) 25742

View more View less

Function(s)
calcium ion binding protein binding identical protein binding protein homodimerization activity S100 protein binding metal ion binding calcium-dependent protein binding ATPase binding zinc ion binding kinase inhibitor activity tau protein binding RAGE receptor binding receptor binding calmodulin-related
Process(es)
negative regulation of transcription from RNA polymerase II promoter regulation of heart contraction substantia nigra development intracellular signal transduction vasodilation positive regulation of sprouting angiogenesis regulation of translation axonogenesis learning or memory memory phosphorylation negative regulation of kinase activity positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of complement activation astrocyte activation regulation of neuronal synaptic plasticity negative regulation of monocyte chemotactic protein-1 production cell adhesion central nervous system development positive regulation of cell proliferation regulation of cell shape positive regulation of myelination positive regulation of apoptotic process response to ethanol positive regulation of neuron differentiation astrocyte differentiation positive regulation of synaptic transmission response to glucocorticoid response to methylmercury long-term synaptic potentiation cellular response to hypoxia response to anesthetic sympathetic neuron projection extension neuron projection extension adaptive thermogenesis negative regulation of skeletal muscle cell differentiation positive regulation of voltage-gated calcium channel activity energy reserve metabolic process cellular calcium ion homeostasis regulation of cytokine biosynthetic process regulation of long-term neuronal synaptic plasticity
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support