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Invitrogen
LIN7C Polyclonal Antibody
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FIGURE: 1 / 4
LIN7C Antibody (51-5600) in ICC/IF
Immunofluorescence analysis of VELI-3 was performed using 70% confluent log phase RSC96 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with LIN7C Rabbit Polyclonal Antibody (Product # 51-5600) at 2µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
51-5600
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Non-human primate,
Rat
Published species
Dog,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the C-terminus of the rat Velis-3 (MALS-3) protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; mammalian LIN-7 3; mammalian lin-seven protein 3; similar to Caenorhabditis elegans LIN-7; unnamed protein product; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; vertebrate LIN7 homolog 3
Gene Aliases: 9130007B12Rik; D2Ertd520e; LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3
UniProt ID: (Human) Q9NUP9, (Rat) Q792I0, (Mouse) O88952
Entrez Gene ID: (Human) 55327, (Dog) 485424, (Rat) 60442, (Mouse) 22343
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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