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Claudin 1 Polyclonal Antibody
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FIGURE: 1 / 70
Claudin 1 Antibody (51-9000) in IHC (P)
Immunohistochemistry analysis of Claudin-1 showing staining in the cytoplasm and membrane of paraffin-embedded human skin tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
51-9000
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Rat
Published species
Amphibian,
Bovine,
C. elegans,
Chicken,
Dog,
Human,
Mouse,
Non-human primate,
Pig,
Rat,
Rodent,
Sheep,
Tag,
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the C-terminus of the human Claudin-1 protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CLDN1; senescence-associated epithelial membrane protein 1; tight junction protein; tight junction transmembrane protein; unnamed protein product
Gene Aliases: CLD1; ILVASC; SEMP1
UniProt ID: (Human) O95832, (Rat) P56745
Entrez Gene ID: (Human) 9076, (Chicken) 424910, (Rat) 65129
establishment of blood-nerve barrier
response to toxic substance
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
positive regulation of cell migration
response to lipopolysaccharide
cell junction maintenance
maintenance of blood-brain barrier
cell-cell junction organization
response to ethanol
viral entry into host cell
protein oligomerization
positive regulation of epithelial cell proliferation involved in wound healing
establishment of skin barrier
xenobiotic transport across blood-nerve barrier
response to interleukin-18
bicellular tight junction assembly
cellular response to lead ion
cellular response to interferon-gamma
cellular response to tumor necrosis factor
response to dexamethasone
cellular response to transforming growth factor beta stimulus
positive regulation of wound healing
establishment of endothelial intestinal barrier
liver regeneration
positive regulation of bicellular tight junction assembly
cellular response to butyrate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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