Search
Rockland
Apolipoprotein C-III Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
Apolipoprotein C-III Antibody (600-101-114) in IHC (P)
Immunohistochemistry of goat anti-Apolipoprotein C-III antibody (Product # 600-101-114). Tissue: human liver. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: Apolipoprotein C-III at 2.5 µg/mL for 1 h at RT. Secondary antibody: Peroxidase goat secondary antibody at 1:10,000 for 45 min at RT. Staining: Apolipoprotein C-III as precipitated red signal with hematoxy... View More
Product Details
600-101-114
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
produced from apoLipoprotein Type C-III derived from human plasma
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
1 mg
Purification
Affinity chromatography
Storage buffer
0.125M sodium borate, pH 8, with 0.005M EDTA, 0.075M NaCl
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
This product is stable at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
For extended storage mix with an equal volume of glycerol, aliquot contents and freeze at -20°C or below.
Target Information
Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Apo-CIII; Apolipoprotein; Apolipoprotein C-III; apolipoprotein C-III precursor; Apolipoprotein C3; MGC150353; unnamed protein product
Gene Aliases: Apo-C3; ApoC-3; APOC3; APOCIII
UniProt ID: (Human) P02656
Entrez Gene ID: (Human) 345
lipid metabolic process
triglyceride metabolic process
lipid transport
G-protein coupled receptor signaling pathway
negative regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
negative regulation of high-density lipoprotein particle clearance
negative regulation of low-density lipoprotein particle clearance
lipid catabolic process
triglyceride catabolic process
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
high-density lipoprotein particle remodeling
very-low-density lipoprotein particle assembly
chylomicron remnant clearance
lipoprotein metabolic process
cholesterol homeostasis
reverse cholesterol transport
negative regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
negative regulation of lipid catabolic process
negative regulation of cholesterol import
triglyceride homeostasis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support