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NeoBiotechnologies
Pulmonary Surfactant-Associated Protein D (SFTPD) Recombinant Mouse Monoclonal Antibody (rSFTPD/8064)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
6441-MSM10-P0
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rSFTPD/8064
Immunogen
Recombinant fragment (around aa200-375) of human SFTPD protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: Epithelial cells of the lung Skin small intestine or bladder.
Cellular Location: Secreted.
Target Information
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: collectin-7; Collectin7; lung surfactant protein D; PSP-D Surfactant protein D; pulmonary surfactant apoprotein; Pulmonary surfactant associated protein PSP-D; SFTP 4; SFTPD; Surfactant associated protein pulmonary 4; surfactant-associated protein, pulmonary 4
Gene Aliases: COLEC7; PSP-D; SFTP4; SP-D
UniProt ID: (Human) P35247
Entrez Gene ID: (Human) 6441
regulation of cytokine production
receptor-mediated endocytosis
negative regulation of interleukin-2 production
negative regulation of T cell proliferation
defense response to bacterium
surfactant homeostasis
innate immune response
macrophage chemotaxis
lung alveolus development
positive regulation of phagocytosis
reactive oxygen species metabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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