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NeoBiotechnologies
SLC18A2 Monoclonal Antibody (SLC18A2/7983)
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Product Details
6571-MSM3-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2, kappa
Class
Monoclonal
Type
Antibody
Clone
SLC18A2/7983
Immunogen
Recombinant fragment of human SLC18A2 protein (exact sequence is proprietary)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: adrenal gland or tonsil. Human brain
Cellular Location: Cytoplasm. Vesicle membrane.
Target Information
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; Solute carrier family 18 member 2; synaptic vesicle amine transporter, brain; synaptic vesicle monoamine transporter, brain; Synaptic vesicular amine transporter; unnamed protein product; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2
Gene Aliases: PKDYS2; SLC18A2; SVAT; SVMT; VAT2; VMAT2
UniProt ID: (Human) Q05940
Entrez Gene ID: (Human) 6571
response to amphetamine
serotonin secretion by mast cell
histamine secretion by mast cell
neurotransmitter transport
serotonin transport
chemical synaptic transmission
locomotory behavior
response to toxic substance
post-embryonic development
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
dopamine transport
serotonin uptake
histamine uptake
establishment of localization in cell
transmembrane transport
neurotransmitter loading into synaptic vesicle
somato-dendritic dopamine secretion
hydrogen ion transmembrane transport
negative regulation of reactive oxygen species biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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