Search
Proteintech
EIF3D Monoclonal Antibody (2C5A3)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
66024-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2C5A3
Immunogen
EIF3D Fusion Protein Ag18092 (323-531 aa encoded by BC000328)
Conjugate
Form
Liquid
Concentration
0.78 mg/mL
Amount
117 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FSQQCLRMG KERYNFPNPN PFVEDDMDKN EIASVAYRYR RWKLGDDIDL IVRCEHDGVM TGANGEVSFI NIKTLNEWDS RHCNGVDWRQ KLDSQRGAVI ATELKNNSYK LARWTCCALL AGSEYLKLGY VSRYHVKDSS RHVILGTQQF KPNEFASQIN LSVENAWGIL RCVIDICMKL EEGKYLILKD PNKQVIRVYS LPDGTFSSDE (323-531 aa encoded by BC000328)
Target Information
eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: eIF-3-zeta; eIF-3-zeta {ECO:0000255|HAMAP-Rule:MF_03003}; eIF3 p66; eIF3-p66; eIF3d; eIF3d {ECO:0000255|HAMAP-Rule:MF_03003}; EIF3S7; Eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255|HAMAP-Rule:MF_03003}; Eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D {ECO:0000255|HAMAP-Rule:MF_03003}; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; RP5-1119A7.12-003; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit; unnamed protein product
Gene Aliases: 66/67kDa; AA407891; eIF3-p66; eIF3-zeta; EIF3D; eIF3p66; EIF3S7
UniProt ID: (Human) O15371, (Rat) Q6AYK8, (Mouse) O70194
Entrez Gene ID: (Human) 8664, (Rat) 362952, (Mouse) 55944
formation of cytoplasmic translation initiation complex
cytoplasmic translational initiation
cap-dependent translational initiation
translation
translational initiation
IRES-dependent viral translational initiation
viral translational termination-reinitiation
formation of translation preinitiation complex
regulation of translational initiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support