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Proteintech
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Immunogen sequence: MAITQFRLF KFCTCLATVF SFLKRLICRS GRGRKLSGDQ ITLPTTVDYS SVPKQTDVEE WTSWDEDAPT SVKIEGGNGN VATQQNSLEQ LEPDYFKDMT PTIRKTQKIV IKKREPLNFG IPDGSTGFSS RLAATQDLPF IHQSSELGDL DTWQENTNAW EEEEDAAWQA EEVLRQQKLA DREKRAAEQQ RKKMEKEAQR LMKKEQNKIG VKLS (1-213 aa encoded by BC017729)
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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