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Proteintech
STAT2 Monoclonal Antibody (1G12C4)
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Product Details
66485-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1G12C4
Immunogen
STAT2 Fusion Protein Ag10168 (503-851 aa encoded by BC051284)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QFSSYVGRG LNSDQLSMLR NKLFGQNCRT EDPLLSWADF TKRESPPGKL PFWTWLDKIL ELVHDHLKDL WNDGRIMGFV SRSQERRLLK KTMSGTFLLR FSESSEGGIT CSWVEHQDDD KVLIYSVQPY TKEVLQSLPL TEIIRHYQLL TEENIPENPL RFLYPRIPRD EAFGCYYQEK VNLQERRKYL KHRLIVVSNR QVDELQQPLE LKPEPELESL ELELGLVPEP ELSLDLEPLL KAGLDLGPEL ESVLESTLEP VIEPTLCMVS QTVPEPDQGP VSQPVPEPDL PCDLRHLNTE PMEIFRNCVK IEEIMPNGDP LLAGQNTVDE VYVSRPSHFY TDGPLMPSDF (503-851 aa encoded by BC051284)
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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