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          • Primary Antibodies ›
          • ERMN Antibodies

          Proteintech

          ERMN Monoclonal Antibody (2B1C1)

          2 References
          View all (5) ERMN antibodies

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          Cite ERMN Monoclonal Antibody (2B1C1)

          Additional Information:
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          • Antibody Testing Data (2)
          ERMN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ERMN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          ERMN Antibody (66605-1-IG) in IHC (P)

          Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 66605-1-IG (ERMN antibody) at dilution of 1:300 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          ERMN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ERMN Antibody in Western Blot (WB)
          ERMN Monoclonal Antibody (2B1C1)

          Product Details

          66605-1-IG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:6,000
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:150-1:600
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Pig, Rat

          Host/Isotype

          Mouse / IgG2b

          Class

          Monoclonal

          Type

          Antibody

          Clone

          2B1C1

          Immunogen

          ERMN Fusion Protein Ag27040 (1-257 aa encoded by BC026345)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          The predicted MW of ERMN is 33 kDa, while western blot analyses of different tissue lysates using 66605-1-Ig antibody to ERMN detected a 50 kDa single band protein as a result of phosphorylation modification.

          Immunogen sequence: MTDVPATFT QAECNGDKPP ENGQQTITKI SEELTDVDSP LPHYRVEPSL EGALTKGSQE ERRKLQGNML LNSSMEDKML KENPEEKLFI VHKAITDLSL QETSADEMTF REGHQWEKIP LSGSNQEIRR QKERITEQPL KEEEDEDRKN KGHQAAEIEW LGFRKPSQAD MLHSKHDEEQ KVWDEEIDDD DDDNCNNDED EVRVIEFKKK HEEVSQFKEE GDASEDSPLS SASSQAVTPD EQPTLGKKSD ISRNAYSR (1-257 aa encoded by BC026345)

          Target Information

          ERMIN plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. ERMIN may play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: cytoskeletal actin-binding protein; Ermin; ermin, ERM-like protein; JN; Juxtanodin; unnamed protein product

          View more View less

          Gene Aliases: A330104H05Rik; AI854460; ermin; ERMN; JN; juxtanodin; KIAA1189; mKIAA1189; RGD1308367

          View more View less

          UniProt ID: (Human) Q8TAM6, (Mouse) Q5EBJ4, (Rat) Q5RJL0

          View more View less

          Entrez Gene ID: (Pig) 100627261, (Human) 57471, (Mouse) 77767, (Rat) 295619

          View more View less

          Function(s)
          actin binding protein binding actin filament binding
          Process(es)
          morphogenesis of a branching structure actin filament organization regulation of cell shape regulation of cell projection organization
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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