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Invitrogen
FOXG1 Recombinant Rabbit Monoclonal Antibody (2H7L2)
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FIGURE: 1 / 4
FOXG1 Antibody (702554) in ICC/IF
For immunofluorescence analysis, U-87 MG cells were fixed and permeabilized for detection of endogenous FOXG1 using Anti-FOXG1 Recombinant Rabbit Monoclonal Antibody (Product # 702554, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of FOXG1 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S3... View More
Product Details
702554
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
2H7L2
Immunogen
Peptides corresponding to human FOXG1 (aa 473-487, 2-15)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Mouse
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
FOXG1B belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of FOXG1B has not yet been determined; however, it may play a role in the development of the brain and telencephalonThis gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BF-1; BF-2; Brain factor 1; Brain factor 2; forkhead box G1B; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; forkhead-like 1; forkhead-like 2; forkhead-like 3; forkhead-like 4; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; FoxG1; HBF-3; HFK1; HFK2; HFK3; HNF-3/forkhead homolog, brain factor 1; oncogene QIN
Gene Aliases: 2900064B05Rik; BF-1; BF1; BF2; FHKL3; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1; FOXG1A; FOXG1B; FOXG1C; HBF-1; HBF-2; HBF-3; HBF-G2; HBF2; Hfh9; Hfhbf1; HFK1; HFK2; HFK3; KHL2; QIN
UniProt ID: (Human) P55316, (Mouse) Q60987
Entrez Gene ID: (Human) 2290, (Mouse) 15228
negative regulation of transcription from RNA polymerase II promoter
positive regulation of neuroblast proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
regulation of mitotic cell cycle
dorsal/ventral pattern formation
regulation of gene expression
axon midline choice point recognition
pyramidal neuron migration
central nervous system neuron development
cerebral cortex development
neurogenesis
forebrain development
inner ear morphogenesis
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
neuron fate determination
cell morphogenesis involved in neuron differentiation
regulation of cell cycle
regulation of neural precursor cell proliferation
regulation of transcription from RNA polymerase II promoter
neuroblast proliferation
brain development
central nervous system neuron differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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