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FIGURE: 1 / 3
Synaptojanin 1 Antibody (711821) in IHC (F)
Immunofluorescence analysis of mouse brain tissue: Frozen sections were fixed with 4% PFA for 20 min, permeabilized using 0.1% Triton-X 100 for 10 mins and blocked for 1 hour with 2% BSA. Transverse sections of mouse brain were incubated with Anti-Synaptojainin 1 Recombinant Rabbit Superclonal™ Antibody (Product # 711821, 1:250 dilution) overnight at 4°C, followed by Goat anti-Rabbit IgG (Heavy Chain) Super... View More
Product Details
711821
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Immunogen
Protein corresponding to human Synaptojanin 1 [aa1156-aa1286]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Monkey, Dog, Horse
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.
Target Information
Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inositol 5'-phosphatase (synaptojanin 1); inositol polyphosphate-5-phosphatase G; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; Synaptojanin-1; synaptojanin-1, polyphosphoinositide phosphatase; unnamed protein product
Gene Aliases: A930006D20Rik; AA675315; DEE53; EIEE53; INPP5G; KIAA0910; mKIAA0910; PARK20; SYNJ1
UniProt ID: (Human) O43426, (Rat) Q62910
Entrez Gene ID: (Human) 8867, (Rat) 85238, (Mouse) 104015
nucleic acid binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
protein binding
hydrolase activity
phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
nucleotide binding
protein C-terminus binding
SH3 domain binding
protein complex binding
phosphoric ester hydrolase activity
phosphatase
lipid metabolic process
phosphatidylinositol biosynthetic process
neurotransmitter transport
endocytosis
learning
synaptic vesicle priming
synaptic vesicle uncoating
phosphatidylinositol-3-phosphate biosynthetic process
inositol phosphate metabolic process
phosphatidylinositol metabolic process
phosphatidylinositol dephosphorylation
synaptic vesicle endocytosis
synaptic vesicle transport
membrane organization
positive regulation of endosome organization
brain development
positive regulation of gliogenesis
response to retinoic acid
response to cytokine
inositol phosphate dephosphorylation
positive regulation of receptor-mediated endocytosis
dephosphorylation
phosphatidylinositol-mediated signaling
positive regulation of synaptic vesicle recycling
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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