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Invitrogen
ADAMTS1 Polyclonal Antibody
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FIGURE: 1 / 1
ADAMTS1 Antibody (720329) in WB
Western blot analysis was performed on Whole cell extracts (30 µg lysate) of HeLa (Lane 1), U-87 MG (Lane 2), PC-3 (Lane 3), NTERA-2 (Lane 4) and tissue extracts of Mouse Liver (Lane 5). The blots were probed with Anti-ADAMTS-1 Rabbit Polyclonal Antibody (Product # 720329, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 61 kDa band corresponding to ADAMTS-1 was observed across the cell lines and tissues test... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
720329
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptides corresponding to Human ADAMTS1 (aa 337-351, 465-479)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 30% glycerol
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Pig and Sheep
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; ADAMTS1; extracellular protein with metalloprotease and TSP domains; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; metalloprotease and thrombospondin-1; METH-1; unnamed protein product
Gene Aliases: ADAM-TS1; ADAMTS; ADAMTS-1; C3-C5; METH-1; METH1
UniProt ID: (Human) Q9UHI8, (Mouse) P97857
Entrez Gene ID: (Human) 9510, (Mouse) 11504
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
negative regulation of angiogenesis
extracellular matrix organization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
ovulation from ovarian follicle
kidney development
positive regulation of neuron projection development
heart trabecula formation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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