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Antibodies Inc
FGF13/FHF2 Monoclonal Antibody (N91/27), FL490
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Product Details
75-134-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N91/27
Immunogen
Fusion protein amino acids 53-245 of human FGF13a (accession number Q92913) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF-13; FGF13A; FGFA; FHF-2; FHF2-1A; FHF2-1B; Fibroblast growth factor; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1; hFHF-2(1X+1W+1V); hFHF-2(1Z+1Y); unnamed protein product
Gene Aliases: DEE90; FGF-13; FGF13; FGF2; FHF-2; FHF2; LINC00889; XLID110
UniProt ID: (Human) Q92913, (Mouse) P70377
Entrez Gene ID: (Human) 2258, (Mouse) 14168
MAPK cascade
neuron migration
sodium ion transport
negative regulation of microtubule depolymerization
signal transduction
cell-cell signaling
nervous system development
learning or memory
learning
memory
hippocampus development
cerebral cortex cell migration
neurogenesis
establishment of neuroblast polarity
microtubule polymerization
negative regulation of collateral sprouting
branching morphogenesis of a nerve
protein localization to plasma membrane
regulation of cardiac muscle cell action potential involved in regulation of contraction
inhibitory synapse assembly
positive regulation of voltage-gated sodium channel activity
apoptotic process
cell proliferation
positive regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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