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LRRK2 WT Full Length Protein

Catalog number:  A15197

Related applications:

Protein Assays and Analysis

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Description

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease.

Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
Uncover novel compounds or hits specific to the full-length form
Advance Parkinson's research using the full-length protein and validated assays

Related Links:
LRRK2 Tools for Advancing Parkinson's Disease Research
LanthaScreen® Kinase Activity Assay
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_940980.3
Expression System: Baculovirus
Protein Form: Full Length
Research Category: Neurobiology
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 120892
Molecular Weight: 288 kDa
Quantity: 10μg
Gene Alias: AURA17, DARDARIN, PARK8, RIPK7, ROCO2
KinaseFamily: LRRK Kinase Family
Protein Tag: DYKDDDDK

Contents & storage

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.