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Thermo Scientific™

YES1 Recombinant Human Protein

Catalog number:  A15558

Related applications:

Protein Assays and Analysis

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Description

YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.

Active—this protein can be used in kinase activity assays, such as Z’-LYTE® assays, or in a binding assay platform like the LanthaScreen® Eu Kinase Binding Assay (KBA).

Purified—purity is determined by gel electrophoresis and provided in lot-specific certificate of analysis (COA).

GST-tagged—provides animal origin flexibility. When used in the KBA platform, it can be paired with a goat- or rabbit-derived Eu-anti-GST antibody.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_005424
Kinase Group: Tyrosine Kinases
Expression System: Baculovirus
Form: Frozen
Protein Form: Full Length
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 88.3 kDa
Gene Alias: YES1
KinaseFamily: SRC Kinase Family
Protein Tag: GST Tag

Contents & storage

50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% glycerol.

For maximum recovery please spin prior to use. Aliquoting the 5 µg, 10 µg, and 20 µg sizes of kinase is not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots; aliquots below 20 µL are not recommended. Never store a kinase diluted. If properly stored at -80°C, this product is guaranteed for 6 months from date of purchase.