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Bethyl Laboratories
TRIP11/TRIP230 Polyclonal Antibody
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FIGURE: 1 / 1
TRIP11/TRIP230 Antibody (A301-188A) in WB
Detection of human TRIP11/TRIP230 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-TRIP11/TRIP230 antibody (Product # A301-188A) used for WB at 0.04 µg/mL (A) and 0.1 µg/mL (B) and used for IP at 3 µg/mg lysate. TRIP11/TRIP230 was also immunoprecipitated by rabbit anti-TRIP11/TRIP230 antibody A301-187A, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure ti... View More
Product Details
A301-188A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1929 and 1979 of Human thyroid hormone receptor interactor 11 (thyroid hormone receptor interactor, 230 kDa).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Clonal evolution-related gene on chromosome 14 protein; GMAP-210; Golgi-associated microtubule-binding protein 210; Golgi-microtubule-associated protein of 210 kDa; thyroid receptor interactor; Thyroid receptor-interacting protein 11; TR-interacting protein 11; Trip230
Gene Aliases: ACG1A; CEV14; GMAP-210; GMAP210; ODCD; ODCD1; TRIP-11; TRIP11; TRIP230
UniProt ID: (Human) Q15643
Entrez Gene ID: (Human) 9321
ventricular septum development
chondrocyte differentiation involved in endochondral bone morphogenesis
transcription from RNA polymerase II promoter
protein glycosylation
ER to Golgi vesicle-mediated transport
Golgi organization
positive regulation of transcription, DNA-templated
cartilage development
inner ear receptor stereocilium organization
bone development
protein transmembrane transport
Golgi ribbon formation
vesicle tethering to Golgi
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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