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          • Primary Antibodies ›
          • PHC3 Antibodies

          Bethyl Laboratories

          PHC3 Polyclonal Antibody

          View all (8) PHC3 antibodies

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          Cite PHC3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          PHC3 Antibody in Western Blot (WB)
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          PHC3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          PHC3 Antibody (A301-569A) in WB

          Detection of human PHC3 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PHC3 antibody (Product # A301-569A) (lot A301-569A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PHC3 Antibody in Western Blot (WB)
          PHC3 Antibody in Immunoprecipitation (IP)
          PHC3 Polyclonal Antibody

          Product Details

          A301-569A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunoprecipitation (IP)

          2-5 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 700 and 750 of human polyhomeotic like 3.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          tris citrate/phosphate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Based on 100% sequence identity, this antibody is predicted to react with Mouse

          Target Information

          Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: early development regulator 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3; member of polycomb family; polycomb group protein; polyhomeotic like 3; Polyhomeotic-like protein 3; unnamed protein product

          View more View less

          Gene Aliases: EDR3; HPH3; PH3; PHC3

          View more View less

          UniProt ID: (Human) Q8NDX5

          View more View less

          Entrez Gene ID: (Human) 80012

          View more View less

          Function(s)
          DNA binding chromatin binding protein binding zinc ion binding histone binding metal ion binding
          Process(es)
          negative regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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