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Bethyl Laboratories
TIGAR Polyclonal Antibody
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FIGURE: 1 / 1
TIGAR Antibody (A302-285A) in WB
Detection of human TIGAR by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-TIGAR antibody (Product # A302-285A) used for WB at 0.1 µg/mL (A) and 1 µg/mL (B) and used for IP at 10 µg/mg lysate. TIGAR was efficiently immunoprecipitated by rabbit anti-TIGAR antibody A302-286A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 se... View More
Product Details
A302-285A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 25 and 75 of Human TP53-induced glycolysis and apoptosis regulator.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fructose-2,6-bisphosphatase TIGAR; fructose-2,6-bisphosphate 2-phosphatase; probable fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; transactivated by NS3TP2 protein; unnamed protein product
Gene Aliases: C12orf5; FR2BP; TIGAR
UniProt ID: (Human) Q9NQ88
Entrez Gene ID: (Human) 57103
mitophagy
response to ischemia
fructose 2,6-bisphosphate metabolic process
glycolytic process
autophagy
apoptotic process
response to stress
cellular response to DNA damage stimulus
response to xenobiotic stimulus
response to gamma radiation
cardiac muscle cell apoptotic process
positive regulation of cardiac muscle cell apoptotic process
glucose catabolic process to lactate via pyruvate
regulation of programmed cell death
negative regulation of programmed cell death
regulation of pentose-phosphate shunt
positive regulation of DNA repair
negative regulation of glycolytic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of phosphate metabolic process
intestinal epithelial cell development
cellular response to cobalt ion
cellular response to hypoxia
reactive oxygen species metabolic process
negative regulation of macromitophagy
regulation of response to DNA damage checkpoint signaling
positive regulation of hexokinase activity
negative regulation of glucose catabolic process to lactate via pyruvate
positive regulation of pentose-phosphate shunt
negative regulation of reactive oxygen species metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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