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Bethyl Laboratories
IRF2 Polyclonal Antibody
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FIGURE: 1 / 3
IRF2 Antibody (A303-380A-T) in WB
Detection of mouse IRF2 by western blot. Samples: Whole cell lysate (50 µg) from NIH 3T3, RAW 264.7, and CH27 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-IRF2 antibody (Product # A303-380A lot 2) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with an exposure time of 75 seconds.
Product Details
A303-380A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 150 and 200 of mouse Interferon Regulatory Factor 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
IRF2 belongs to the interferon regulatory factor family. IRF2 regulates the transcription regulation important to cell proliferation as well as immune responses by binding to the upstream regulatory region of type I IFN and IFNinducible MHC class I genes (the interferon consensus sequence (ICS)) and repression of those genes. However, IRF2 also functions as a transcriptional activator of histone H4 by interactions with NF-kappa B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686F0244; Interferon regulatory factor 2; IRF-2; IRF2; OTTHUMP00000218576; OTTHUMP00000218580; unnamed protein product
Gene Aliases: 9830146E22Rik; AI646973; IRF-2; IRF2
UniProt ID: (Human) P14316, (Mouse) P23906
Entrez Gene ID: (Human) 3660, (Mouse) 16363
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
regulatory region DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
immune system process
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell proliferation
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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