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Bethyl Laboratories
ARPC2 Polyclonal Antibody
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FIGURE: 1 / 2
ARPC2 Antibody (A305-394A) in WB
Detection of human and mouse ARPC2 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ARPC2 antibody (Product # A305-394A) (lot A305-394A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A305-394A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 175 to 225 of human Actin-related protein 2/3 complex subunit 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Orangutan
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 34 kD subunit of the Arp2/3 protein complex; actin related protein 2/3 complex, subunit 2, 34kDa; Actin-related protein 2/3 complex subunit 2; Arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34; NB4 apoptosis/differentiation related protein; p34-ARC; testis tissue sperm-binding protein Li 53e; unnamed protein product
Gene Aliases: 2210023N03Rik; 34kDa; ARC34; ARPC2; p34-Arc; PNAS-139; PRO2446
UniProt ID: (Human) O15144, (Mouse) Q9CVB6
Entrez Gene ID: (Human) 10109, (Mouse) 76709
positive regulation of lamellipodium assembly
actin filament polymerization
positive regulation of actin filament polymerization
Arp2/3 complex-mediated actin nucleation
positive regulation of cellular component biogenesis
positive regulation of cellular component organization
actin polymerization-dependent cell motility
positive regulation of substrate adhesion-dependent cell spreading
regulation of actin filament polymerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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