Invitrogen™

AXL Recombinant Human Protein

Catalog number:  A31521

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Description

AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma. The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation.

The purified recombinant protein can be used in a number of different applications, but it has been specifically validated for use with both the LanthaScreen™ & Z'-LYTE™ assay technologies to identify novel kinase inhibitors. AXL is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the LanthaScreen & Z'-LYTE assay technology
• Available in multiple pack sizes for convenient use
• Also available in our SelectSceen Kinase Profiling Service

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Research Category: Drug Development
Accession Number: NP_068713.2
Gene Aliases: JTK11, UFO
Molecular Weight: 48.3 kDa
Product Size: 1 mg
Protein Length or Portion (a.a.): 473 - end
Protein Tag or Fusion: His Tag
Species: Human
Validated Application: Kinase Assay
Expression: Insect
Kinase Family: AXL Kinase Family
Protein Form: Active, Cytoplasmic, Recombinant, Truncated
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol

Store at -80°C. Upon first use, aliquot and store at -80°C to avoid multiple freeze/thaws.

Documents

Manuals & protocols