Efficient-Pro AGT Medium is a next-generation Chinese hamster ovary (CHO) medium used in the production of monoclonal antibodies (mAbs), offering significant performance and ease-of-use improvements over earlier Gibco and competitor products. Designed to work optimally with Efficient-Pro AGT Feed 1 and Efficient-Pro AGT Feed 2 for use in CHO-K1 and DG-44/CHO-S cell lines respectively, the Efficient-Pro AGT system increases titer and specific productivity, improves protein quality and metabolite profiles, and is easier to use with less solubility issues than other CHO media and feed offerings.
Efficient-Pro AGT system will help you:
• Benefit from the ease-of-use associated with Gibco’s trademarked, patented Advanced Granulation technology (AGT) for auto-pH and simplified dissolution
• Sustain cell viability for longer bioreactor runs and maximized titer
• Improve downstream outputs such as protein glycosylation, charge-variants, and aggregation
• Speed up process development and streamline transfer to manufacturing scale
• Increase flexibility with a range of format and packaging configurations
• Decrease cell shock with simplified adaptation protocols
Efficient-Pro AGT Medium has been formulated as a chemically defined, animal-origin-free cell culture medium used in the bioproduction of mAbs and other therapeutics in traditional batch and fed-batch bioprocessing workflows, particularly in combination with CHO cell line variants. The proprietary AGT format is the only one of its kind in the industry and is the most advanced media format available in the market.
Efficient-Pro AGT Medium is a balanced formulation designed to meet the metabolic needs of mAb production and does not contain growth factors or insulin to ensure batch-to-batch consistency and production efficiency. Demonstrated to improve productivity in a CHO-K1 cell line when paired with Efficient-Pro AGT Feed 1 compared to an industry-leader’s media and feed system, the Efficient-Pro AGT system helps accelerate your time-to-market and achieve success.