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Invitrogen
DPM1 Monoclonal Antibody (5C5A7)
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FIGURE: 1 / 12
DPM1 Antibody (A-6429) in WB
The Journal of biological chemistry 2022 -
Purification of vac uole from WT, atg15Delta , and atg15Delta atg2Delta cells. A , schematic representation of the purification of autophagic bodies from vacuoles. B , phase-contrast microscopy images of vacuole fractions. After 3 h of induction of autophagy by rapamycin, vacuoles were isolated from WT, atg15 Delta, and atg15 Delta atg2 Delta cells. Scale bars represent 2 mum. C , Western blotting of the wh... View More
Product Details
A-6429
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Yeast
Published species
Human,
Yeast
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5C5A7
Immunogen
Yeast Dolichol phosphate mannose synthase
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
250 µg
Purification
purified
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dolichol-phosphate mannose synthase; Dolichol-phosphate mannosyltransferase; Dolichyl-phosphate beta-D-mannosyltransferase; DPM synthase; Mannose-P-dolichol synthase; MPD synthase; OTTMUSP00000017164; RP23-391M18.1
Gene Aliases: DPM1; P9705.3; SED3; YPR183W
UniProt ID: (Baker's yeast) P14020
Entrez Gene ID: (Baker's yeast) 856313
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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