Search

  • Contáctenos
  • Orden Rápida

Bethyl Laboratories

CGRP Recombinant Rabbit Monoclonal Antibody (BLR159J)

View all (26) CGRP antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation'] || 'Additional Information'}}: {{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:

{{$ctrl.translations[$ctrl.isSkuNotesCollapsed ? 'antibody.pdp.skuNotes.viewMore' : 'antibody.pdp.skuNotes.viewLess']}}
CGRP Recombinant Rabbit Monoclonal Antibody (BLR159J)

Product Details

A700-159

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

BLR159J

Immunogen

Peptide representing a region between residue 75 and 125 of mouse Calcitonin gene-related Peptide 1.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

250 µg/mL

Amount

25 µg

Purification

purified

Storage buffer

BBS, pH 8.2, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Target Information

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: alpha-type CGRP; calcitonin gene-related peptide I; MGC126648; neuropeptide; alpha-CGRP; RAT calcitonin; unnamed protein product

View more View less

Gene Aliases: CA; Calc; Calc1; Cgrp; CGRP-1; CGRP1; Ct; Ctn

View more View less

UniProt ID: (Mouse) P70160

View more View less

Entrez Gene ID: (Mouse) 12310

View more View less

Function(s)
receptor binding hormone activity calcitonin receptor binding identical protein binding macromolecular complex binding
Process(es)
endothelial cell proliferation vasculature development neurological system process involved in regulation of systemic arterial blood pressure vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure regulation of heart rate G-protein coupled receptor internalization monocyte chemotaxis protein phosphorylation cellular calcium ion homeostasis inflammatory response leukocyte cell-cell adhesion adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuropeptide signaling pathway embryo implantation feeding behavior response to heat negative regulation of calcium ion transport into cytosol negative regulation of ossification receptor internalization negative regulation of neurological system process activation of protein kinase activity positive regulation of interleukin-1 alpha production positive regulation of interleukin-8 production vasodilation endothelial cell migration positive regulation of macrophage differentiation negative regulation of osteoclast differentiation negative regulation of blood pressure positive regulation of ossification negative regulation of bone resorption negative regulation of transcription, DNA-templated negative regulation of smooth muscle contraction sperm capacitation response to pain detection of temperature stimulus involved in sensory perception of pain regulation of cytosolic calcium ion concentration calcitonin family receptor signaling pathway amylin receptor 1 signaling pathway amylin receptor 2 signaling pathway cellular response to nerve growth factor stimulus calcitonin gene-related peptide receptor signaling pathway
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support