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Bethyl Laboratories
NF-H Recombinant Rabbit Monoclonal Antibody (BLR190J)
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Product Details
A700-190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
BLR190J
Immunogen
Peptide representing a region between residue 1040 and the C-terminus (residue 1090) of mouse neurofilament heavy.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
50 µg/mL
Amount
5 µg
Purification
purified
Storage buffer
BBS, pH 8.2, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 200 kDa neurofilament protein; NEF3; neurofilament; neurofilament 200kDa; neurofilament triplet H protein; NF 200 kD; Nfh; NF200; NHC
Gene Aliases: mKIAA0845; NF-H; NF200; Nfh
UniProt ID: (Mouse) P19246
Entrez Gene ID: (Mouse) 380684
microtubule cytoskeleton organization
ovarian follicle atresia
axonogenesis
axon regeneration
neurofilament bundle assembly
intermediate filament cytoskeleton organization
intermediate filament bundle assembly
peripheral nervous system neuron axonogenesis
neurofilament cytoskeleton organization
axon development
postsynaptic modulation of chemical synaptic transmission
postsynaptic intermediate filament cytoskeleton organization
regulation of organelle transport along microtubule
response to sodium arsenite
cellular response to leukemia inhibitory factor
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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