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Bethyl Laboratories

ThPOK Recombinant Rabbit Monoclonal Antibody (BLR191J)

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ThPOK Recombinant Rabbit Monoclonal Antibody (BLR191J)

Product Details

A700-191

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

Flow Cytometry (Flow)

0.5 µL/10^6 cells
-

Immunoprecipitation (IP)

20 µL/mg of lysate
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

BLR191J

Immunogen

Peptide representing a region between residue 250 and 300 of Human ThPOK (aka Zinc finger and BTB domain-containing protein 7B).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

250 µg/mL

Amount

25 µg

Purification

purified

Storage buffer

BBS, pH 8.2, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Immunocytochemistry: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Target Information

ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DKFZp686G01254; krueppel-related zinc finger protein cKrox; RP11-307C12.9; T-helper-inducing POZ/Krueppel-like factor; unnamed protein product; Vzinc finger and BTB domain containing 7B; zinc finger and BTB domain containing 15; zinc finger protein 67; zinc finger protein 67 homolog; zinc finger protein 857B; zinc finger protein Th-POK; zinc-finger transcription factor

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Gene Aliases: c-KROX; CKROX; hcKROX; THPOK; vGAF; ZBTB15; ZFP-67; ZFP67; ZNF857B

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UniProt ID: (Human) O15156, (Mouse) Q64321

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Entrez Gene ID: (Human) 51043, (Mouse) 22724

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding identical protein binding protein homodimerization activity histone deacetylase binding sequence-specific double-stranded DNA binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter NK T cell differentiation regulation of transcription from RNA polymerase II promoter lactation regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of interleukin-17 production response to insulin regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of CD4-positive, alpha-beta T cell differentiation regulation of CD8-positive, alpha-beta T cell differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation positive regulation of fat cell differentiation positive regulation of transcription from RNA polymerase II promoter positive regulation of insulin receptor signaling pathway negative regulation of NK T cell proliferation positive regulation of brown fat cell differentiation positive regulation of cold-induced thermogenesis adaptive thermogenesis negative regulation of T-helper 17 cell differentiation positive regulation of SREBP signaling pathway transcription from RNA polymerase II promoter ectoderm development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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