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Alomone Labs, LTD
Ephrin-B2 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
Ephrin-B2 (extracellular) Antibody (AER-042-25UL) in IHC (F)
Expression of Ephrin-B2 in rat hippocampus. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-Ephrin-B2 (extracellular) Antibody (#AER-042) (1:200), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal dentate gyrus region, showed immunoreactivity (green) in astrocytes of the hilus (H, arrows) and in neurons of the granule layer (G). B. Pre-incubation... View More
Product Details
AER-042-25UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide HIREHEPPGALTELD, corresponding to amino acid residues 368-382 of mouse NRROS. Extracellular, N-terminus.
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: HIREHEPPGALTELD
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELF-2; EPH-related receptor tyrosine kinase ligand 5; Ephrin-B2; HTK ligand; HTK-L; LERK-5; ligand of eph-related kinase 5; ligand of the eph-related receptor tyrosine kinases hek and elk; MGC126226; MGC126227; MGC126228
Gene Aliases: EFNB2; ELF-2; Elf2; ephrin-B2; Epl5; EPLG5; Htk-L; HTKL; LERK-5; LERK5; NLERK-1
UniProt ID: (Human) P52799, (Mouse) P52800
Entrez Gene ID: (Human) 1948, (Mouse) 13642, (Rat) 306636
angiogenesis
lymph vessel development
cell migration involved in sprouting angiogenesis
cell adhesion
nervous system development
axon guidance
positive regulation of cell proliferation
anatomical structure morphogenesis
organ morphogenesis
negative regulation of keratinocyte proliferation
negative regulation of neuron projection development
cell differentiation
T cell costimulation
adherens junction organization
keratinocyte proliferation
viral entry into host cell
ephrin receptor signaling pathway
blood vessel morphogenesis
venous blood vessel morphogenesis
regulation of chemotaxis
cellular response to lipopolysaccharide
nephric duct morphogenesis
presynapse assembly
regulation of postsynaptic membrane neurotransmitter receptor levels
regulation of postsynaptic neurotransmitter receptor internalization
positive regulation of aorta morphogenesis
positive regulation of cardiac muscle cell differentiation
multicellular organism development
cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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