[Differential expression profile of microRNA between hyperplastic scar and normal skin].
AuthorsNing P, Liu DW, Mao YG, Peng Y, Lin ZW, Liu DM,
JournalZhonghua Yi Xue Za Zhi
PubMed ID22781298
To explore the miRNA differential expression profiles of hyperplastic scar and normal skin so as to further elucidate the pathogenesis of hyperplastic scar and search for new therapeutic targets. The total RNA was extracted from 5 human hyperplastic scar and normal skin tissues by Trizol. The specimens were collected from ... More
Circulating microRNAs in serum: novel biomarkers for patients with bladder cancer?
AuthorsScheffer AR, Holdenrieder S, Kristiansen G, von Ruecker A, Müller SC, Ellinger J,
JournalWorld J Urol
PubMed ID23266581
'PURPOSE: Recent studies indicate that circulating microRNAs in serum/plasma are a novel class of non-invasive biomarkers with diagnostic and prognostic information. So far, circulating microRNAs have not been analyzed in patients with bladder cancer. METHODS: We collected serum from patients with non-muscle invasive bladder cancer (NMIBC), muscle invasive bladder cancer ... More
[Isolation, identification and analysis of the expression profile of miRNAs in Aedes albopictus].
AuthorsZheng PM, Wu JY, Gu JB, Tu ZJ, Chen XG,
JournalNan Fang Yi Ke Da Xue Xue Bao
PubMed ID20423824
'To verify the miRNA in Aedes albopictus and characterize the expression profile of several miRNAs across all the life stages of Aedes albopictus. Based on the published miRNA sequences of Anopheles gambiae and Aedes aegypti, 6 DIG-labeled antisense probes were synthesized. The total RNAs from Aedes albopictus in 6 developmental ... More
MicroRNA expression profiles in the progression of prostate cancer-from high-grade prostate intraepithelial neoplasia to metastasis.
AuthorsLeite KR, Tomiyama A, Reis ST, Sousa-Canavez JM, Sañudo A, Camara-Lopes LH, Srougi M,
JournalUrol Oncol
PubMed ID21880514
'Models of the multistep process related to cancer progression have been designed for many cancers including prostate. The aim of this study is to propose a new model including a possible role for recently described micro RNAs in prostate cancer (CaP) progression. Sixty-three patients underwent radical prostatectomy to treat localized ... More
A model for data analysis of microRNA expression in forensic body fluid identification.
AuthorsWang Z, Luo H, Pan X, Liao M, Hou Y,
JournalForensic Sci Int Genet
PubMed ID21903498
MicroRNAs (miRNAs, 18-25 bases in length) are small, non-coding RNAs that regulate gene expression at the post-transcriptional level. MiRNA expression patterns, including presence and relative abundance of particular miRNA species, provide cell- and tissue-specific information that can be used for body fluid identification. Recently, two published studies reported that a ... More
High resolution of microRNA signatures in human whole saliva.
AuthorsPatel RS, Jakymiw A, Yao B, Pauley BA, Carcamo WC, Katz J, Cheng JQ, Chan EK,
JournalArch Oral Biol
PubMed ID21704302
Identifying discriminatory human salivary RNA biomarkers reflective of disease in a low-cost non-invasive screening assay is crucial to salivary diagnostics. Recent studies have reported both mRNA and microRNA (miRNA) in saliva, but little information has been documented on the quality and yield of RNA collected. Therefore, the aim of the ... More